Inter Milan had both centre backs sent off in the first half but the ultra-tough Serie A leaders still battled to a 0-0 home draw with Sampdoria on Saturday.
Photos from soccer matches played across top European Leagues on Saturday.
Premier League leaders Manchester City face a tricky match at Napoli but they would also advance to the next stage with victory in southern Italy.
Diego Forlan is to leave La Liga club Atletico Madrid after four seasons and will join Serie A side Inter Milan, the Uruguay striker announced on Monday.
Napoli shot to the top of Serie A with a controversial 3-0 win at 10-man Inter Milan on Saturday as Claudio Ranieri suffered his first defeat in charge and was sent off at halftime.
David Beckham can look forward to a return to Old Trafford after AC Milan were drawn against his former club Manchester United in the last 16 of the Champions League on Friday. Friday's draw also pitted Jose Mourinho, now coach of Inter Milan, with his old club Chelsea.
AC Milan forward Antonio Cassano is set to join Inter, with Giampaolo Pazzini moving in the opposite direction, the two clubs said on Tuesday.
Mbappe struck in the 74th minute to put PSG on 80 points from 29 games and on the brink of retaining the title with second-placed Lille, who beat Nantes 3-2 away earlier on Sunday, still 20 points behind having played a game more.
Juventus's Montenegro striker Mirko Vucinic has been left out of their squad for the trip to Lazio in Serie A on Saturday (1945 GMT) after his move to Inter Milan fell through this week.
Inter Milan President Massimo Moratti has been banned from running the club for three months for discussing a transfer deal with suspended Genoa owner Enrico Preziosi.
Real Madrid forward Cristiano Ronaldo has shaken off his relatively poor early-season form in perfect time for Tuesday's Champions League Group G clash with fellow European giants AC Milan.
Juventus moved top with 19 points to Inter's 18 and it was a deserved victory in an absorbing contest.
Rui Patricio saved three penalties as Wolverhampton Wanderers defeated English Premier League champions Manchester City to claim the Premier League Asia Trophy 3-2 in a penalty shootout.
The English Premier League title race was thrown wide open with leaders Manchester United losing a second successive match and Liverpool thumping Aston Villa 5-0 to close the gap at the top to one point. Barcelona maintained their six-point lead in Spain, while a double from Zlatan Ibrahimovic ensured Inter Milan stayed seven points clear in Serie A.
AC Milan's season slumped to a new low on Sunday as they had two players sent off and lost 2-1 at Udinese while the bizarre postponement of the Cagliari-AS Roma match further damaged Serie A's fading credibility.
Serie A leaders Inter Milan handed Genoa their first home league defeat of the season on Saturday when strikers Zlatan Ibrahimovic and Mario Balotelli sealed a hard-fought 2-0 victory. With 11 games left, the champions stay seven points clear of second-placed Juventus, who beat city rivals Torino 1-0 thanks to Giorgio Chiellini's 81st minute header from a Pavel Nedved free kick.
Inter Milan gave Roberto Mancini his first Serie A victory since returning as coach a month ago when they won 2-0 in soggy conditions at Chievo on Monday.
Inter Milan should be basking in the glory of a record-breaking season but instead the manner of Jose Mourinho's departure has left a nasty taste in the mouth.
Samuel Eto'o shone once again with both goals in Inter Milan's 2-1 comeback win at Palermo to send the champions joint top of Serie A on Sunday.
Forgotten man Massimo Oddo, only playing because of a raft of injuries, set up both goals to send AC Milan up to second in Serie A after an action-packed 2-1 win at 10-man Napoli in heavy rain on Monday.
Inter Milan landed a massive blow in the Serie A title tussle on Sunday, going nine points clear when they beat AC Milan 2-0 in a high voltage derby which they finished with nine men.
Inter Milan battled to a 2-1 win over an impressive Chelsea to hold a slight advantage after their Champions League last-16 first leg at the San Siro on Wednesday.
Italian champions Inter Milan probably have more attacking options than any other team in Europe except Barcelona and they finally believe they can make a mark on the Champions League this season.
Javier Zanetti made his 800th appearance for Inter Milan in the Italians' 2-0 win at Romania's Vaslui in a Europa League tie on Thursday.
Inter Milan's unhappy run continued when they were held to a 1-1 draw at home by lowly Chievo in Serie A on Monday and were jeered off the San Siro pitch by their own fans
Samuel Eto'o scored a scintillating home hat-trick for holders Inter Milan in the Champions League on Wednesday as former Barcelona teammate Lionel Messi's magic went missing in a 1-1 draw in Russia.
champions Inter Milan are now three points clear at the top of Serie A with 17 points from seven games courtesy of their 2-1 win over Napoli.
'It was a long career, really long, thank you to everyone who gave me the strength, the adrenaline and the emotion to continue.'
Images from the football matches played across Europe on Wednesday.
Sampdoria sank champions Inter Milan 1-0 with a second-half Giampaolo Pazzini goal to go top of Serie A on Saturday.
Barcelona teenager Ansu Fati scored twice to lead his side to a 2-1 win at home to Levante on Sunday, finding the net in a league game for the first time in more than four months and becoming the youngest player to net a La Liga double. Romelu Lukaku scored a quickfire second-half double to give Inter Milan a 2-0 win at Udinese on Sunday, ending their run of three successive 1-1 league draws.
The move would end a turbulent spell at the club for the Argentine, who has fallen out with fans along on the way and provided fodder for the gossip columns thanks to his marriage to Wanda Nara, a media personality who also acts as his agent.
Tottenham Hotspur trounced a sorry Inter Milan 3-0 in the Europa League on Thursday while last year's European champions Chelsea were humbled 1-0 by Steaua Bucharest after being stung by a Raul Rusescu penalty.
Inter Milan's shy striker Diego Milito finally hit the global headlines on Saturday with two superb goals to clinch the European Cup having previously gone about his business almost unnoticed in the wider world.
Real Madrid took full advantage of slip-ups from the chasing pack by beating Villarreal 3-2 to move nine points clear in the Spanish Primera Liga.
AC Milan clung on to beat Parma 5-4 away in Serie A on Sunday despite an dreadful defensive display which included Mattia De Sciglio scoring an extraordinary own goal from near the halfway line late in the match.
Now only Inter stand in the way of a treble that would match Manchester United's still unique feat of 1999.
The world's best player Lionel Messi lit up the opening night of the Champions League for Barcelona although holders Inter Milan and Manchester United endured less than sparkling starts on Tuesday.
Saturday's Champions League final between Bayern Munich and Inter Milan is so much more than just one game of soccer with a myriad of intertwined storylines promising an intriguing night whatever happens on the field.